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PATIENT GUIDE

PLI: evidence and pregnancy-loss care

Paternal lymphocyte immunization (PLI), also called lymphocyte immunization therapy, appears on some fertility websites. Being advertised does not establish that a treatment is effective.

What the evidence says

ESHRE recommends against lymphocyte immunization therapy for unexplained recurrent pregnancy loss because benefit has not been demonstrated and serious adverse effects are possible.

A more useful consultation

Bring records of previous pregnancies, investigations and treatments. Ask what assessment is appropriate, which findings would change your care and what evidence supports any proposed add-on.

Questions about pli: evidence and pregnancy-loss care

Use these pages to prepare your questions. The clinic can confirm details for your appointment.

Sources and further reading

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